Armodafinil Tablets

Armodafinil Tablets

Armodafinil Tablets

Armodafinil is a central nervous system stimulant eugeroic drug with a half-life of approximately 15 hours. As a single-enantiomer derivative of modafinil, armodafinil 150 mg demonstrates potent wakefulness-promoting properties. Armodafinil is primarily prescribed for the treatment of excessive daytime sleepiness caused by narcolepsy or shift work sleep disorder, as well as obstructive sleep apnea and hypopnea syndrome.

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Action mechanism of Armodafinil tablet involves the inhibition of dopamine reuptake and the stimulation of certain neurotransmitters, leading to increased alertness and cognitive performance. Armodafinil 150 mg has been reported to exhibit minimal side effects and drug interactions, making it a valuable option for patients requiring enhanced wakefulness and cognitive function. Armodafinil tablets are sold under the brand name Waklert 150 mg & Artvigil 150 mg.

What are The Uses of Armodafinil Tablets?

The main purpose of the medication armodafinil 150 mg is to treat excessive daytime sleepiness, which is associated with different types of sleep disorders. Its uses include:

Narcolepsy

Armodafinil is approved for the treatment of narcolepsy, which is a chronic neurological disorder that includes symptoms such as excessive daytime sleepiness, sudden episodes of muscle weakness (cataplexy), hallucinations, and sleep paralysis.

Obstructive Sleep Apnea (OSA)

OSA is a condition where breathing repeatedly stops and starts during sleep due to obstruction of the upper airway. Armodafinil is prescribed to promote wakefulness and reduce daytime sleepiness in patients with this disorder.

Shift Work Sleep Disorder (SWSD)

People who work non-traditional hours, such as night shifts or rotating shifts, may experience disruptions in their sleep-wake cycle. Armodafinil can help individuals with SWSD stay awake and alert during their work hours and maintain a more regular sleep schedule during non-working hours.

What are The Dosage Guidelines for Armodafinil Tablets?

The recommended dose is 150 mg orally once daily in the morning.

  • Narcolepsy/OSA

Morning administration improves wakefulness.

  • SWSD

Take 1 hour pre-shift for enhanced alertness.

How to Take a Armodafinil Tablet?
  • Armodafinil tablets should be taken orally with a full glass of water.
  • It can be taken with or without food.
  • The tablet should be swallowed whole and not crushed, chewed, or divided.
Missed Dosage Guidelines
  • If you forget to take your Armodafinil dose, you should take it as soon as you remember, unless it is almost time for your next dose.
  • When the next dose is almost due, the missed dose should not be taken. Instead, the regular dosing schedule should be started again.
  • In order to make up for a missed dose, you should not take two doses at once.
Overdosage Guidelines
  • In the event of an overdose, individuals should promptly seek medical assistance or call a poison control center. 
  • Anxiety, insomnia, confusion, hallucinations, and, in the worst cases, seizures can be signs of an overdose.
  • Supportive care and symptomatic treatment under medical supervision may be used to treat an overdose.

Guidelines to Buy Prescription (Schedule IV Controlled Substance) Drugs Online

Armodafinil 150  mg is a medication that is used to treat narcolepsy and obstructive sleep apnea. It is a Schedule IV-controlled substance. So, these medications need a prescription to buy online in the United States of America (USA), the United Kingdom (UK), Europe (EU) & Australia (AU). So, buy Armodafinil tablets in the United States of America (USA), the United Kingdom (UK), Europe (EU) & Australia (AU) only if you are prescribed with this medication. Reputable pharmacy can provide generic Armodafinil like Waklert 150mg tablets with low price guarantee, free pills, free shipping, and secured payment methods like credit card, debit card, ZellePay, bitcoin, etc.

How does Armodafinil Tablet Work?

Armodafinil tablet is a wakefulness enhancing medicine used in people with drowsiness due to narcolepsy or obstructive sleep apnea & daytime sleepiness due to shift work sleep disorder. It work by changing the activity of neurotransmitters in the brain, especially dopamine, norepinephrine, and serotonin. The ability to regulate your sleep and wake cycles depends on these chemicals. Although its exact mechanism of action is unknown, armodafinil is believed to stimulate dopamine release in the prefrontal cortex and hypothalamus, two areas of the brain. One of the important neurotransmitters is dopamine, which controls mood,motivation, and alertness. This drug also raises the levels of chemicals such as norepinephrine and serotonin. This helps with wakefulness, focus, and mood control. Unlike most stimulants, armodafinil does not cause jitteriness and does not really mess up your sleep patterns. It is efficacious in addressing excessive daytime sleepiness associated with narcolepsy, obstructive sleep apnea (OSA), and shift work sleep disorder (SWSD). The fact that armodafinil can change neurotransmitter levels shows how well it works as a drug to help people who have trouble sleeping stay awake. Researchers are still looking into its intricate mechanisms of action.

What are The Side Effects of Armodafinil Tablets?

Headache, nausea, insomnia, dizziness, anxiety, dry mouth, elevated blood pressure, palpitations, and rash are some of the common side effects of armodafinil 150 mg.

There are some severe, while less common, side effects given below.

Allergic reactions 

Armodafinil can cause severe allergic reactions that manifest as rash, itching, swelling (especially of the face, tongue, or throat), extreme dizziness, or difficulty breathing. These require immediate medical attention.

Serious skin reactions

Armodafinil has been linked to some rare but serious skin reactions, such as Stevens-Johnson syndrome and toxic epidermal necrolysis. An itch, blisters, and peeling skin are some of the signs. 

Psychiatric symptoms

While taking Armodafinil, some people may have severe mental health problems like hallucinations, agitation, aggressive behavior, depression, or thoughts of suicide. If any of these symptoms show up, you should seek medical attention right away.

Cardiovascular effects

Armodafinil could have very bad effects on the heart and blood vessels, such as chest pain, an irregular heartbeat, or signs of a heart attack. Getting medical help right away is necessary if any cardiovascular symptoms happen.

Liver problems

Armodafinil has been linked to very few cases of liver problems, such as hepatitis and high liver enzymes. Your skin or eyes may turn yellow, your urine may be dark, or you may feel sick and vomit all the time. When these symptoms show up, you need to see a doctor right away.

Precautions & Warnings:

Keep in mind the precautions for the following special cases before consuming Armodafinil:

  • Allergies- The patient must inform the physician if they have ANY allergies. Even though a patient might not be allergic to armodafinil, they might be allergic to the inactive ingredients.
  • Liver or kidney disease patients- Allergic reactions to Armodafinil might affect organs like liver and kidney. Patients with liver and kidney disorders must inform their doctor.
  • Heart disease patients- Patients suffering from or the history of- Left ventricular hypertrophy and Mitral valve prolapse should not use Armodafinil. They must inform their doctors if they have these or any other heart conditions.
  • Women using contraceptives- Armodafinil affects the efficiency of hormonal contraceptives. Hence, women must switch to other methods of contraceptives during Armodafinil treatment.
  • Pregnant and breastfeeding women- there is no evidence about any adverse effect of Armodafinil on the growing foetus. There is also no evidence about the drug being found in breastmilk. However, pregnant and breastfeeding women must consult their doctors before use.
  • Psychotic patients- Patients suffering from psychotic issues might have an overreaction due to consumption of Armodafinil. These patients must inform their doctors in advance.

General warnings before taking Armodafinil:

  • The patient must take Armodafinil only under doctor’s prescription.
  • They must inform the doctors about any heart conditions
  • The drug must not be taken along with alcohol or controlled substances. Patients with a history of alcohol and/or substance abuse must inform the doctor.
  • People consuming Armodafinil must avoid driving heavy vehicles. Armodafinil is a stimulant drug. Although there are no cases of accidents, there are possibilities that the drug impairs judgement.
  • Patients must never share Armodafinil with other people, especially those with a history of substance abuse.
  • Patients must not change the dose or stop taking the drug on their own will.

Interactions:

Reproductive hormones

Armodafinil blocks the CYP3A4/5 enzymes in the liver, which break down estrogen and progestins. This can make hormonal birth control methods like pills, patches, and rings less effective. 

It is advised to use non-hormonal contraceptive alternatives while taking Armodafinil and for a minimum of one month following its discontinuation.

Antifungal Medications

Some antifungal medications, such as itraconazole and ketoconazole, have the ability to inhibit the metabolism of armodafinil, which could increase the drug’s blood levels and adverse effect risk. Consider changing the dose of Armodafinil if it is being used with these other drugs.

CYP3A4 Inducers/Inhibitors

Cytochrome P450 enzymes, especially CYP3A4/5, are the main ones that break down armodafinil.

It may be necessary to exercise caution and adjust dosages when co-administering Armodafinil with CYP3A4 inducers (such as rifampin, carbamazepine) or inhibitors (such as clarithromycin, ritonavir). 

CNS Depressants

Armodafinil has the potential to intensify the effects of CNS depressants such as benzodiazepines, alcohol, opioids, and sedative-hypnotics. 

Psychiatric Medications

Psychiatric medication interactions, such as those involving SSRIs, TCAs, MAOIs, and antipsychotics, can result in agitation, serotonin syndrome, or a rise in mental health symptoms. It may be essential to closely monitor and adjust the dosage.

Cardiovascular Medications

Armodafinil can cause an increase in heart rate and blood pressure, particularly in those who are vulnerable. If this medication is taken together with cardiovascular drugs, physicians advise us to monitor blood pressure and make changes to required dosage.

Smoking Tobacco

According to research, smoking speeds up the metabolism of armodafinil, which could lower plasma concentrations and effectiveness.

FAQs:

Q. How long does it take for Armodafinil 150 mg to start working?

After taking it orally, armodafinil 150 mg typically starts to work one to two hours later. The start of action may be a little different for each person. 

Q. How should I take Armodafinil 150mg tablets?

You should take armodafinil 150 mg pills by mouth with a full glass of water, usually once a day in the morning. It’s okay to take them with or without food. For the best results, it’s important to follow your healthcare provider’s dosage guidelines.

Q. Should I drink alcohol while taking Armodafinil 150 mg??

Drinking booze while taking Armodafinil 150 mg is usually not a good idea or should be limited. While taking Armodafinil, drinking alcohol may make the effects stronger on the central nervous system, making you feel more sleepy or dizzy.

Q. Who cannot take armodafinil 150 mg?

Armodafinil 150 mg should not be taken by individuals who have a known hypersensitivity or allergy, pregnant or breastfeeding women, paediatric patients with severe liver impairment, or cardiovascular conditions.

Q. What will happen if an anxiety patient consumes Armodafinil with anxiety medications?

You might get serotonin syndrome or become agitated if you take Armodafinil with anxiety medicines. Consult a healthcare provider.

Q. What is the chemical formula of armodafinil 150 mg?

The chemical formula of armodafinil is C15H15NO2S.

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